Orenthal James Simpson ( – ), also known by his nickname "the Juice", was an American professional football player, actor, and media personality who played in the National Football League (NFL) for 11 seasons, primarily with the Buffalo Bills. OJSimpson, the high-profile football player accused of killing his wife in the 1990s, has died at 76 years old following a short battle with prostate cancer, suggesting his disease spread quickly. The family of OJSimpson have confirmed that the former NFL star has died after a battle with prostate cancer at the age of 76. The retired American footballer rose to prominence during a glittering spell with the Buffalo Bills, solidifying his reputation as one of the sport’s greatest-ever running backs. The family of OJSimpson, the former NFL star who was accused of double murder, has confirmed his causeofdeath at the age of 76. Simpson had a remarkable career in American football, particularly during his time with the Buffalo Bills, where he established himself as one of the sport's... O.J. SimpsonCauseOfDeath Revealed. Exclusive. 60.O.J. Simpson's official causeofdeath has been revealed ... one of the most infamous, high-profile Americans of all time died from prostate cancer, TMZ has learned. Simpson had a legendary NFL career (Image: Getty). Thirteen years later in 2008, Simpson was sentenced to 33 years imprisonment on charges of armed robbery and was only released in 2017 on parole after serving a minimum of nine years. OJSimpson Died After a ‘Battle With Cancer,’ His Family Wrote, Announcing His CauseofDeath. On April 10th, our father, Orenthal James Simpson, succumbed to his battle with cancer. O.J. Simpson, the renowned former football star famously accused and subsequently acquitted of the 1994 murders of his ex-wife and her friend, has passed away at the age of 76. OJSimpson Is Dead at 76.TMZ Sports says it got the confirmation from Simpson's longtime attorney and executor of his estate, Malcolm LaVergne, who said he received a copy of Simpson's death certificate with verification.